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smFRET Kinetic Model

Three-state OIC kinetic model for single-molecule FRET data with bleaching-aware ensemble fitting.

Code License: BSD-3-Clause Figures & Plots License: CC BY 4.0 Python >=3.11 codecov

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Quick start

pip install -e ".[dev,docs]"
python get_traces.py --data-dir data/Hugel_2025 --export-dir data/timeseries
python pipeline.py --outdir results --multistarts 5 --bootstraps 10 --cores 4