Abhinav Mishra

You can view my complete CV as PDF here.


Education

  • Master of Science, Bioinformatics
    Freie Universität Berlin, Germany — 2025
    Thesis: Mathematical Optimization of Signalling Networks in Triple Negative Breast Cancer Cell Lines

  • Bachelor of Technology, Bioinformatics
    Jaypee University of Information Technology, India — 2017
    Thesis: Identification of Potent Biomarkers for Prostate Cancer Through AR, MAPK, and mTOR Signalling Pathway Mining


Experience

  • Research Intern — Institute for Biology, HU Berlin (Jan 2025 – Feb 2025)
    Developed a physiologically based pharmacokinetic model for Tirzepatide using curated clinical data and parameter optimization.
    GitHub

  • Master Thesis Student — Theoretical Biophysics, HU Berlin (May 2024 – Jan 2025)
    Built and validated an optimization framework to reconstruct triple-negative breast cancer phosphorylation networks from LC-MS and kinase-substrate data using Differential Evolution and Sequential Least Squares Programming.
    GitHub

  • Bachelor Thesis Student — JUIT, India (Feb 2016 – Mar 2017)
    Designed a pipeline using GEO2R, MeV, WB-DEGS, and R/Shiny to identify and validate prostate cancer biomarkers.
    GitHub

  • Project Researcher — JUIT, India (Aug 2015 – Mar 2016)
    Developed a docking workflow with Discovery Studio, Maestro, and Glide XP to screen FDA-approved drugs against the Dopamine D3 receptor. Analyzed interactions using PyMol & VMD.
    GitHub


Software & Tools

See Projects for details.


Publications

  • Mishra, A. & König, M. Physiologically Based Pharmacokinetic (PBPK) Model of Tirzepatide. Zenodo, 2025. DOI
  • Asati, N., Mishra, A., Shukla, A., Singh, T. Gene Expression Studies to Identify Significant Genes in AR, MTOR, MAPK Pathways and their Overlapping Regulatory Role in Prostate Cancer. J. Integrative Bioinformatics, 16(3), 2019. DOI

Awards & Honours

  • 3rd Prize, Poster Presentation, NSCSB 2016, JUIT India
  • GATE Qualified, All India Rank 681 (2018)

Community & Membership

  • Administrator, BioBaes (since 2020)
    Non-profit community for bioinformatics enthusiasts. Focused on mentoring, open knowledge, and creating accessible opportunities.

  • Member, International Society for Computational Biology (ISCB) — 1 year


My Technical Toolkit

Development Environment

VS Code PyCharm Conda Poetry

Workflow & Version Control

Nextflow Docker GNU Make Git

Programming Languages

Python R Bash Perl C++

Reproducibility & Documentation

Jupyter LaTeX Markdown Quarto Read the Docs